AFH Automated Fluid Handling System


Automated Fluid Handling System

Alfa Wassermann's fluid handling system fully automates and standardizes the critical process of fluid filling and fractionation in a self-contained mobile work station.

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AFH software comes pre-loaded with standard fluid handing protocols. Custom protocols that include sanitation, rinsing, filling, fractionation and other methods can be programed on site by the user. Network integration is available to utilize upstream/downstream inputs and outputs via open platform communication (OPC).

System design includes:
Fluid routing pinch valves
Flow rate and direction control pump
Flow, pressure, and temperature product sensors

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AFH Automated Fluid Handling System
Fully automated filling and fractionation of ultracentrifuge density gradient process.
Compact, mobile and self-contained with reservoir and process bag storage shelf.
Operator programmable standard and customized process steps,
Real time display and stored reporting of critical process parameters.

Benefits of Automated Fluid Management

Standard and customizable processes
  • Model existing SOP’s
  • Repeatable sequences without variation can result in more consistent batches
  • Simplifies operator training
  • Reduces procedural errors that can result in rejected batches
Domain authentication of system operators
  • Eliminate the need for special operator databases and database maintenance by integrating with existing facility security policies
SQL Server database stores all methods, batch data and audit logs
  • All information is stored locally in a 21 CFR Part 11 compliant database
  • Access to all data is provided to the facility system administrator
Storage and real time monitoring of critical parameters: pressure, flowrate, temperature, weight, Brix value and density
  • Warns operator of out of limit conditions potentially saving costly batch loss
  • Stored databases for easy access to previous batch parameters
Integrated OPC Server
  • Network integration allows the AFH fluid handling system to react to and respond to other facility equipment
  • Batch records integrated with facility data history
IP65 enclosures, non-contact pump, pressure transducers and temperature monitors
  • System can be cleaned without special preparation
  • Disposable Class VI refractometer flow cell (PES material) reduces cost
  • Optional stainless steel 316 flow cell for easy cleaning
  • Specific customer instrumentation can be integrated into the fluid handling system

Our Mission

To be the supplier whose singular purpose is the support of bioprocess and pharmaceutical industries by providing expertise in continuous flow UCF separation applications and now fluid handling solutions.

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Alfa Wassermann Inc . 4 Henderson Drive
West Caldwell . NJ 07006 . USA

Telephone +1 800 220 4488
Fax +1 973 276 0383


Alfa Wassermann B.V. Lorentzlaan 5
3401 MX IJsselstein . Netherlands

Telephone +31 348 487 300
Fax +31 348 433 000